Unfulfilled desire for children
If pregnancy cannot be achieved using the woman’s own oocytes, egg donation offers the most promising conditions for a successful pregnancy outcome.
Egg donation is the treatment of choice under the following conditions:
- After surgical removal of both ovaries
- After chemotherapy and radiation therapy of the lesser pelvis
- Following the treatment of malignant diseases
- Condition referred to as premature menopause, i.e. premature ovarian failure = POF
- Genetic disorders
- Repeated incidence of pathological alterations in embryos during previous IVF/ICSI attempts
- Repeated failure of fertilization in the course of previous IVF/ICSI treatments
- Repeated negative pregnancy tests after the transfer of “good quality” embryos
In any case, a functioning uterus is a crucial requirement when considering egg donation.
The uterus is prepared with estrogen and gestagen, either orally or by intramuscular or transdermal injections, to mimic the normal structure of the endometrial mucosa. It is fairly easy to achieve pregnancy through egg donation, provided that the recipient has a normal uterus and the donor is ideally under 32 years and can provide healthy oocytes.